Human ANAPC13 activation kit by CRISPRa

CAT#: GA108582

ANAPC13 CRISPRa kit - CRISPR gene activation of human anaphase promoting complex subunit 13

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ANAPC13
• Locus ID: 25847
• Kit Components:

  GA108582G1, ANAPC13 gRNA vector 1 in pCas-Guide-CRISPRa

  GA108582G2, ANAPC13 gRNA vector 2 in pCas-Guide-CRISPRa

  GA108582G3, ANAPC13 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001242374, NM_001242375, NM_015391, NR_024400, NR_024401
• Synonyms: APC13; SWM1
• Summary: This gene encodes a component of the anaphase promoting complex, a large ubiquitin-protein ligase that controls cell cycle progression by regulating the degradation of cell cycle regulators such as B-type cyclins. The encoded protein is evolutionarily conserved and is required for the integrity and ubiquitin ligase activity of the anaphase promoting complex. Pseudogenes and splice variants have been found for this gene; however, the biological validity of some of the splice variants has not been determined. [provided by RefSeq, Nov 2008]