Human DFNB31 (WHRN) activation kit by CRISPRa

CAT#: GA108591

WHRN CRISPRa kit - CRISPR gene activation of human whirlin

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: WHRN
• Locus ID: 25861
• Kit Components:

  GA108591G1, WHRN gRNA vector 1 in pCas-Guide-CRISPRa

  GA108591G2, WHRN gRNA vector 2 in pCas-Guide-CRISPRa

  GA108591G3, WHRN gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001083885, NM_001173425, NM_015404, NM_001346890
• Synonyms: CIP98; PDZD7B; USH2D; WHRN; WI
• Summary: This gene is thought to function in the organization and stabilization of sterocilia elongation and actin cystoskeletal assembly, based on studies of the related mouse gene. Mutations in this gene have been associated with autosomal recessive non-syndromic deafness and Usher Syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2016]