Human Protein Kinase D2 (PRKD2) activation kit by CRISPRa

CAT#: GA108594

PRKD2 CRISPRa kit - CRISPR gene activation of human protein kinase D2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PRKD2
• Locus ID: 25865
• Kit Components:

  GA108594G1, PRKD2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA108594G2, PRKD2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA108594G3, PRKD2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001079880, NM_001079881, NM_001079882, NM_016457
• Synonyms: HSPC187; nPKC-D2; PKD2
• Summary: The protein encoded by this gene belongs to the protein kinase D (PKD) family of serine/threonine protein kinases. This kinase can be activated by phorbol esters as well as by gastrin via the cholecystokinin B receptor (CCKBR) in gastric cancer cells. It can bind to diacylglycerol (DAG) in the trans-Golgi network (TGN) and may regulate basolateral membrane protein exit from TGN. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]