Human HDPTP (PTPN23) activation kit by CRISPRa

CAT#: GA108639

PTPN23 CRISPRa kit - CRISPR gene activation of human protein tyrosine phosphatase non-receptor type 23

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PTPN23
• Locus ID: 25930
• Kit Components:

  GA108639G1, PTPN23 gRNA vector 1 in pCas-Guide-CRISPRa

  GA108639G2, PTPN23 gRNA vector 2 in pCas-Guide-CRISPRa

  GA108639G3, PTPN23 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001304482, NM_015466
• Synonyms: HD-PTP; HDPTP; PTP-TD14
• Summary: This gene encodes a member of the non-receptor type protein-tyrosine phosphatase family. The encoded protein may be involved in the regulation of small nuclear ribonucleo protein assembly and pre-mRNA splicing by modifying the survival motor neuron (SMN) complex. The encoded protein additionally plays a role in ciliogenesis and is part of endosomal sorting complex required for transport (ESCRT) pathways. This gene may serve a tumor suppressor function. [provided by RefSeq, Jul 2016]