Human ANKRD25 (KANK2) activation kit by CRISPRa

CAT#: GA108658

KANK2 CRISPRa kit - CRISPR gene activation of human KN motif and ankyrin repeat domains 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: KANK2
• Locus ID: 25959
• Kit Components:

  GA108658G1, KANK2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA108658G2, KANK2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA108658G3, KANK2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001136191, NM_001329451, NM_015493
• Synonyms: ANKRD25; MXRA3; PPKWH; SIP
• Summary: This gene encodes a member of the KN motif and ankyrin repeat domains (KANK) family of proteins, which play a role in cytoskeletal formation by regulating actin polymerization. The encoded protein functions in the sequestration of steroid receptor coactivators and possibly other proteins. Mutations in this gene are associated with impaired kidney podocyte function and nephrotic syndrome, and keratoderma and woolly hair. [provided by RefSeq, Jul 2016]