Human ACOT11 activation kit by CRISPRa

CAT#: GA108704

ACOT11 CRISPRa kit - CRISPR gene activation of human acyl-CoA thioesterase 11

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ACOT11
• Locus ID: 26027
• Kit Components:

  GA108704G1, ACOT11 gRNA vector 1 in pCas-Guide-CRISPRa

  GA108704G2, ACOT11 gRNA vector 2 in pCas-Guide-CRISPRa

  GA108704G3, ACOT11 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_015547, NM_147161
• Synonyms: BFIT; STARD14; THEA; THEM1
• Summary: This gene encodes a member of the acyl-CoA thioesterase family which catalyse the conversion of activated fatty acids to the corresponding non-esterified fatty acid and coenzyme A. Expression of a mouse homolog in brown adipose tissue is induced by low temperatures and repressed by warm temperatures. Higher levels of expression of the mouse homolog has been found in obesity-resistant mice compared with obesity-prone mice, suggesting a role of acyl-CoA thioesterase 11 in obesity. Alternative splicing results in transcript variants. [provided by RefSeq, Nov 2010]