Human SLITRK5 activation kit by CRISPRa

CAT#: GA108722

SLITRK5 CRISPRa kit - CRISPR gene activation of human SLIT and NTRK like family member 5

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SLITRK5
• Locus ID: 26050
• Kit Components:

  GA108722G1, SLITRK5 gRNA vector 1 in pCas-Guide-CRISPRa

  GA108722G2, SLITRK5 gRNA vector 2 in pCas-Guide-CRISPRa

  GA108722G3, SLITRK5 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_015567
• Synonyms: bA364G4.2; LRRC11
• Summary: Members of the SLITRK family, such as SLITRK5, are integral membrane proteins with 2 N-terminal leucine-rich repeat (LRR) domains similar to those of SLIT proteins (see SLIT1; MIM 603742). Most SLITRKs, including SLITRK5, also have C-terminal regions that share homology with neurotrophin receptors (see NTRK1; MIM 191315). SLITRKs are expressed predominantly in neural tissues and have neurite-modulating activity (Aruga et al., 2003 [PubMed 14557068]). [supplied by OMIM, Mar 2008]