Human Kallikrein 13 (KLK13) activation kit by CRISPRa

CAT#: GA108741

KLK13 CRISPRa kit - CRISPR gene activation of human kallikrein related peptidase 13

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: KLK13
• Locus ID: 26085
• Kit Components:

  GA108741G1, KLK13 gRNA vector 1 in pCas-Guide-CRISPRa

  GA108741G2, KLK13 gRNA vector 2 in pCas-Guide-CRISPRa

  GA108741G3, KLK13 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_015596, NM_001348177, NM_001348178, NR_145463, NR_145464, NR_145465, NR_145466, NR_145467
• Synonyms: KLK-L4; KLKL4
• Summary: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Expression of this gene is regulated by steroid hormones and may be useful as a marker for breast cancer. [provided by RefSeq, Jan 2017]