Human WIPI2 activation kit by CRISPRa

CAT#: GA108753

WIPI2 CRISPRa kit - CRISPR gene activation of human WD repeat domain, phosphoinositide interacting 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: WIPI2
• Locus ID: 26100
• Kit Components:

  GA108753G1, WIPI2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA108753G2, WIPI2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA108753G3, WIPI2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001033518, NM_001033519, NM_001033520, NM_001278299, NM_015610, NM_016003
• Synonyms: ATG18B; Atg21; CGI-50; WIPI-2
• Summary: WD40 repeat proteins are key components of many essential biologic functions. They regulate the assembly of multiprotein complexes by presenting a beta-propeller platform for simultaneous and reversible protein-protein interactions. Members of the WIPI subfamily of WD40 repeat proteins, such as WIPI2, have a 7-bladed propeller structure and contain a conserved motif for interaction with phospholipids (Proikas-Cezanne et al., 2004 [PubMed 15602573]). [supplied by OMIM, Mar 2008]