Human CABYR activation kit by CRISPRa

CAT#: GA108821

CABYR CRISPRa kit - CRISPR gene activation of human calcium binding tyrosine phosphorylation regulated

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CABYR
• Locus ID: 26256
• Kit Components:

  GA108821G1, CABYR gRNA vector 1 in pCas-Guide-CRISPRa

  GA108821G2, CABYR gRNA vector 2 in pCas-Guide-CRISPRa

  GA108821G3, CABYR gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001308231, NM_012189, NM_138643, NM_138644, NM_153768, NM_153769, NM_153770
• Synonyms: CABYRa; CABYRc; CABYRc/d; CABYRe; CBP86; CT88; FSP-2; FSP2
• Summary: To reach fertilization competence, spermatozoa undergo a series of morphological and molecular maturational processes, termed capacitation, involving protein tyrosine phosphorylation and increased intracellular calcium. The protein encoded by this gene localizes to the principal piece of the sperm flagellum in association with the fibrous sheath and exhibits calcium-binding when phosphorylated during capacitation. A pseudogene on chromosome 3 has been identified for this gene. Alternatively spliced transcript variants encoding distinct protein isoforms have been found for this gene. [provided by RefSeq, Jul 2013]