Human Pallidin (BLOC1S6) activation kit by CRISPRa

CAT#: GA108823

BLOC1S6 CRISPRa kit - CRISPR gene activation of human biogenesis of lysosomal organelles complex 1 subunit 6

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: BLOC1S6
• Locus ID: 26258
• Kit Components:

  GA108823G1, BLOC1S6 gRNA vector 1 in pCas-Guide-CRISPRa

  GA108823G2, BLOC1S6 gRNA vector 2 in pCas-Guide-CRISPRa

  GA108823G3, BLOC1S6 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001311255, NM_001311256, NM_012388, NR_132350, NR_132351, NR_132352, NR_132353, NR_132354, NR_132355, NR_132356, NR_132357, NR_132358, NR_132359
• Synonyms: BLOS6; HPS9; PA; PALLID; PLDN
• Summary: The protein encoded by this gene may play a role in intracellular vesicle trafficking. It interacts with Syntaxin 13 which mediates intracellular membrane fusion. Mutations in this gene cause symptoms associated with Hermansky-Pudlak syndrome-9. Alternative splicing results in multiple transcript variants. A pseudogene related to this gene is located on the X chromosome. [provided by RefSeq, Aug 2015]