Human HIBCH activation kit by CRISPRa

CAT#: GA108837

HIBCH CRISPRa kit - CRISPR gene activation of human 3-hydroxyisobutyryl-CoA hydrolase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: HIBCH
• Locus ID: 26275
• Kit Components:

  GA108837G1, HIBCH gRNA vector 1 in pCas-Guide-CRISPRa

  GA108837G2, HIBCH gRNA vector 2 in pCas-Guide-CRISPRa

  GA108837G3, HIBCH gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_014362, NM_198047
• Synonyms: HIBYLCOAH
• Summary: This gene encodes the enzyme responsible for hydrolysis of both HIBYL-CoA and beta-hydroxypropionyl-CoA. Mutations in this gene have been associated with 3-hyroxyisobutyryl-CoA hydrolase deficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]