Human GAPDHS activation kit by CRISPRa

CAT#: GA108855

GAPDHS CRISPRa kit - CRISPR gene activation of human glyceraldehyde-3-phosphate dehydrogenase, spermatogenic

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: GAPDHS
• Locus ID: 26330
• Kit Components:

  GA108855G1, GAPDHS gRNA vector 1 in pCas-Guide-CRISPRa

  GA108855G2, GAPDHS gRNA vector 2 in pCas-Guide-CRISPRa

  GA108855G3, GAPDHS gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_014364
• Synonyms: GAPD2; GAPDH-2; GAPDS; HEL-S-278; HSD-35
• Summary: This gene encodes a protein belonging to the glyceraldehyde-3-phosphate dehydrogenase family of enzymes that play an important role in carbohydrate metabolism. Like its somatic cell counterpart, this sperm-specific enzyme functions in a nicotinamide adenine dinucleotide-dependent manner to remove hydrogen and add phosphate to glyceraldehyde 3-phosphate to form 1,3-diphosphoglycerate. During spermiogenesis, this enzyme may play an important role in regulating the switch between different energy-producing pathways, and it is required for sperm motility and male fertility. [provided by RefSeq, Jul 2008]