Human TIMM13 activation kit by CRISPRa

CAT#: GA108885

TIMM13 CRISPRa kit - CRISPR gene activation of human translocase of inner mitochondrial membrane 13

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TIMM13
• Locus ID: 26517
• Kit Components:

  GA108885G1, TIMM13 gRNA vector 1 in pCas-Guide-CRISPRa

  GA108885G2, TIMM13 gRNA vector 2 in pCas-Guide-CRISPRa

  GA108885G3, TIMM13 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_012458
• Synonyms: ppv1; TIM13; TIM13B; TIMM13A; TIMM13B
• Summary: This gene encodes a member of the evolutionarily conserved TIMM (translocase of inner mitochondrial membrane) family of proteins that function as chaperones in the import of proteins from the cytoplasm into the mitochondrial inner membrane. Proteins of this family play a role in collecting substrate proteins from the translocase of the outer mitochondrial membrane (TOM) complex and delivering them to either the sorting and assembly machinery in the outer mitochondrial membrane (SAM) complex or the TIMM22 complex in the inner mitochondrial membrane. The encoded protein and the translocase of mitochondrial inner membrane 8a protein form a 70 kDa complex in the intermembrane space. [provided by RefSeq, Jul 2013]