Human TIM 1 (HAVCR1) activation kit by CRISPRa

CAT#: GA108942

HAVCR1 CRISPRa kit - CRISPR gene activation of human hepatitis A virus cellular receptor 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: HAVCR1
• Locus ID: 26762
• Kit Components:

  GA108942G1, HAVCR1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA108942G2, HAVCR1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA108942G3, HAVCR1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001099414, NM_001173393, NM_001308156, NM_012206
• Synonyms: HAVCR; HAVCR-1; KIM-1; KIM1; TIM; TIM-1; TIM1; TIMD-1; TIMD1
• Summary: The protein encoded by this gene is a membrane receptor for both human hepatitis A virus (HHAV) and TIMD4. The encoded protein may be involved in the moderation of asthma and allergic diseases. The reference genome represents an allele that retains a MTTVP amino acid segment that confers protection against atopy in HHAV seropositive individuals. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 4, 12 and 19. [provided by RefSeq, Apr 2015]