Human ATP2C1 activation kit by CRISPRa

CAT#: GA108974

ATP2C1 CRISPRa kit - CRISPR gene activation of human ATPase secretory pathway Ca2+ transporting 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ATP2C1
• Locus ID: 27032
• Kit Components:

  GA108974G1, ATP2C1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA108974G2, ATP2C1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA108974G3, ATP2C1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001001485, NM_001001486, NM_001001487, NM_001199179, NM_001199180, NM_001199181, NM_001199182, NM_001199183, NM_001199184, NM_001199185, NM_014382
• Synonyms: ATP2C1A; BCPM; HHD; hSPCA1; PMR1; SPCA1
• Summary: The protein encoded by this gene belongs to the family of P-type cation transport ATPases. This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium ions. Defects in this gene cause Hailey-Hailey disease, an autosomal dominant disorder. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]