Human FOXP1 activation kit by CRISPRa

CAT#: GA108998

FOXP1 CRISPRa kit - CRISPR gene activation of human forkhead box P1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: FOXP1
• Locus ID: 27086
• Kit Components:

  GA108998G1, FOXP1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA108998G2, FOXP1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA108998G3, FOXP1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001012505, NM_001244808, NM_001244810, NM_001244812, NM_001244813, NM_001244814, NM_001244815, NM_001244816, NM_032682, NM_001349337, NM_001349338, NM_001349339, NM_001349340, NM_001349341, NM_001349342, NM_001349343, NM_001349344, NR_146142, NR_146143, NM_001370548
• Synonyms: 12CC4; hFKH1B; HSPC215; MFH; QRF1
• Summary: This gene belongs to subfamily P of the forkhead box (FOX) transcription factor family. Forkhead box transcription factors play important roles in the regulation of tissue- and cell type-specific gene transcription during both development and adulthood. Forkhead box P1 protein contains both DNA-binding- and protein-protein binding-domains. This gene may act as a tumor suppressor as it is lost in several tumor types and maps to a chromosomal region (3p14.1) reported to contain a tumor suppressor gene(s). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]