Human CD57 (B3GAT1) activation kit by CRISPRa

CAT#: GA108999

B3GAT1 CRISPRa kit - CRISPR gene activation of human beta-1,3-glucuronyltransferase 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: B3GAT1
• Locus ID: 27087
• Kit Components:

  GA108999G1, B3GAT1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA108999G2, B3GAT1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA108999G3, B3GAT1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_018644, NM_054025, NM_001367973
• Synonyms: CD57; GLCATP; GLCUATP; HNK1; LEU7; NK-1; NK1
• Summary: The protein encoded by this gene is a member of the glucuronyltransferase gene family. These enzymes exhibit strict acceptor specificity, recognizing nonreducing terminal sugars and their anomeric linkages. This gene product functions as the key enzyme in a glucuronyl transfer reaction during the biosynthesis of the carbohydrate epitope HNK-1 (human natural killer-1, also known as CD57 and LEU7). Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008]