Human CACNG5 activation kit by CRISPRa

CAT#: GA109002

CACNG5 CRISPRa kit - CRISPR gene activation of human calcium voltage-gated channel auxiliary subunit gamma 5

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CACNG5
• Locus ID: 27091
• Kit Components:

  GA109002G1, CACNG5 gRNA vector 1 in pCas-Guide-CRISPRa

  GA109002G2, CACNG5 gRNA vector 2 in pCas-Guide-CRISPRa

  GA109002G3, CACNG5 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_014404, NM_145811
• Synonyms: calcium channel, voltage-dependent, gamma subunit 5; MGC126656; MGC126682; neuronal voltage-gated calcium channel gamma-5 subunit; voltage-dependent calcium channel gamma-5 subunit
• Summary: The protein encoded by this gene is a type II transmembrane AMPA receptor regulatory protein (TARP). TARPs regulate both trafficking and channel gating of the AMPA receptors. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two family members, a type I TARP and a calcium channel gamma subunit. This gene is a susceptibility locus for schizophrenia and bipolar disorder. [provided by RefSeq, Dec 2010]