Human PDE7B activation kit by CRISPRa

CAT#: GA109016

PDE7B CRISPRa kit - CRISPR gene activation of human phosphodiesterase 7B

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PDE7B
• Locus ID: 27115
• Kit Components:

  GA109016G1, PDE7B gRNA vector 1 in pCas-Guide-CRISPRa

  GA109016G2, PDE7B gRNA vector 2 in pCas-Guide-CRISPRa

  GA109016G3, PDE7B gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_018945
• Synonyms: bA472E5.1
• Summary: The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a cAMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. [provided by RefSeq, Apr 2009]