Human FILIP1 activation kit by CRISPRa

CAT#: GA109034

FILIP1 CRISPRa kit - CRISPR gene activation of human filamin A interacting protein 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: FILIP1
• Locus ID: 27145
• Kit Components:

  GA109034G1, FILIP1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA109034G2, FILIP1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA109034G3, FILIP1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001289987, NM_001300866, NM_015687, NR_110608
• Synonyms: FILIP
• Summary: This gene encodes a filamin A binding protein. The encoded protein promotes the degradation of filamin A and may regulate cortical neuron migration and dendritic spine morphology. Mice lacking a functional copy of this gene exhibit reduced dendritic spine length and altered excitatory signaling. [provided by RefSeq, Oct 2016]