Human DIMT1L (DIMT1) activation kit by CRISPRa

CAT#: GA109102

DIMT1 CRISPRa kit - CRISPR gene activation of human DIMT1 rRNA methyltransferase and ribosome maturation factor

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: DIMT1
• Locus ID: 27292
• Kit Components:

  GA109102G1, DIMT1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA109102G2, DIMT1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA109102G3, DIMT1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_014473, NM_001348076, NM_001348077
• Synonyms: DIM1; DIMT1L; HSA9761; HUSSY5
• Summary: The protein encoded by this gene is a methyltransferase that is responsible for dimethylation of adjacent adenosines near the 18S rRNA decoding site. The encoded protein is essential for ribosome biogenesis, although its catalytic activity is not involved in the process. The yeast ortholog of this protein functions in the cytoplasm while this protein functions in the nucleus. [provided by RefSeq, Jan 2017]