Human PCDH11X activation kit by CRISPRa
CAT#: GA109122
PCDH11X CRISPRa kit - CRISPR gene activation of human protocadherin 11 X-linked
Find the corresponding CRISPRi Inhibitor Kit
USD 1,290.00
2 Weeks*
Specifications
Product Data | |
Format | 3gRNAs, 1 scramble ctrl and 1 enhancer vector |
Symbol | PCDH11X |
Locus ID | 27328 |
Kit Components | GA109122G1, PCDH11X gRNA vector 1 in pCas-Guide-CRISPRa GA109122G2, PCDH11X gRNA vector 2 in pCas-Guide-CRISPRa GA109122G3, PCDH11X gRNA vector 3 in pCas-Guide-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100058 |
Disclaimer | The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001168360, NM_001168361, NM_001168362, NM_001168363, NM_014522, NM_032967, NM_032968, NM_032969 |
Synonyms | PCDH-X; PCDH11; PCDHX; PPP1R119 |
Summary | This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The encoded protein consists of an extracellular domain containing 7 cadherin repeats, a transmembrane domain and a cytoplasmic tail that differs from those of the classical cadherins. The gene is located in a major X/Y block of homology and its Y homolog, despite divergence leading to coding region changes, is the most closely related cadherin family member. The protein is thought to play a fundamental role in cell-cell recognition essential for the segmental development and function of the central nervous system. Disruption of this gene may be associated with developmental dyslexia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014] |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN412346 | PCDH11X - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
USD 1,290.00 |
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