PCDH11X Human Gene Knockout Kit (CRISPR)
CAT#: KN412346
PCDH11X - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.
KN2.0 knockout kit validation
KN412346 is the updated version of KN212346.
USD 1,290.00
2 Weeks*
Size
Other products for "PCDH11X"
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 linear donor |
Donor DNA | EF1a-GFP-P2A-Puro |
Symbol | PCDH11X |
Locus ID | 27328 |
Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_001168360, NM_001168361, NM_001168362, NM_001168363, NM_014522, NM_032967, NM_032968, NM_032969 |
Synonyms | PCDH-X; PCDH11; PCDHX; PPP1R119 |
Summary | This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The encoded protein consists of an extracellular domain containing 7 cadherin repeats, a transmembrane domain and a cytoplasmic tail that differs from those of the classical cadherins. The gene is located in a major X/Y block of homology and its Y homolog, despite divergence leading to coding region changes, is the most closely related cadherin family member. The protein is thought to play a fundamental role in cell-cell recognition essential for the segmental development and function of the central nervous system. Disruption of this gene may be associated with developmental dyslexia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014] |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
GA109122 | PCDH11X CRISPRa kit - CRISPR gene activation of human protocadherin 11 X-linked |
USD 1,290.00 |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.