Human MT (MCAT) activation kit by CRISPRa

CAT#: GA109141

MCAT CRISPRa kit - CRISPR gene activation of human malonyl-CoA-acyl carrier protein transacylase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: MCAT
• Locus ID: 27349
• Kit Components:

  GA109141G1, MCAT gRNA vector 1 in pCas-Guide-CRISPRa

  GA109141G2, MCAT gRNA vector 2 in pCas-Guide-CRISPRa

  GA109141G3, MCAT gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_014507, NM_173467, NR_046423
• Synonyms: fabD; FASN2C; MCT; MT; NET62
• Summary: The protein encoded by this gene is found exclusively in the mitochondrion, where it catalyzes the transfer of a malonyl group from malonyl-CoA to the mitochondrial acyl carrier protein. The encoded protein may be part of a fatty acid synthase complex that is more like the type II prokaryotic and plastid complexes rather than the type I human cytosolic complex. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2012]