Human TOR2A activation kit by CRISPRa

CAT#: GA109147

TOR2A CRISPRa kit - CRISPR gene activation of human torsin family 2 member A

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TOR2A
• Locus ID: 27433
• Kit Components:

  GA109147G1, TOR2A gRNA vector 1 in pCas-Guide-CRISPRa

  GA109147G2, TOR2A gRNA vector 2 in pCas-Guide-CRISPRa

  GA109147G3, TOR2A gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001085347, NM_001134430, NM_001134431, NM_001252018, NM_001252021, NM_001252023, NM_130459
• Synonyms: TORP1
• Summary: This gene encodes a member of the AAA family of adenosine triphosphatases with similarity to Clp proteases and heat shock proteins. Alternative splicing at this locus results in the translation of multiple isoforms of the encoded protein, some of which contain salusin peptides in the C-terminal region. These peptides may play roles in hypotension, myocardial growth and the induction of mitogenesis, and may also be involved in the pathogenesis of atherosclerosis. The antimicrobial peptide salusin-beta has antibacterial activity. [provided by RefSeq, Nov 2014]