Human CCDC22 activation kit by CRISPRa

CAT#: GA109164

CCDC22 CRISPRa kit - CRISPR gene activation of human coiled-coil domain containing 22

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CCDC22
• Locus ID: 28952
• Kit Components:

  GA109164G1, CCDC22 gRNA vector 1 in pCas-Guide-CRISPRa

  GA109164G2, CCDC22 gRNA vector 2 in pCas-Guide-CRISPRa

  GA109164G3, CCDC22 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_014008
• Synonyms: CXorf37; JM1; RTSC2
• Summary: This gene encodes a protein containing a coiled-coil domain. The encoded protein functions in the regulation of NF-kB (nuclear factor kappa-light-chain-enhancer of activated B cells) by interacting with COMMD (copper metabolism Murr1 domain-containing) proteins. The mouse orthologous protein has been shown to bind copines, which are calcium-dependent, membrane-binding proteins that may function in calcium signaling. This human gene has been identified as a novel candidate gene for syndromic X-linked intellectual disability. [provided by RefSeq, Aug 2013]