Human IFT81 activation kit by CRISPRa

CAT#: GA109186

IFT81 CRISPRa kit - CRISPR gene activation of human intraflagellar transport 81

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: IFT81
• Locus ID: 28981
• Kit Components:

  GA109186G1, IFT81 gRNA vector 1 in pCas-Guide-CRISPRa

  GA109186G2, IFT81 gRNA vector 2 in pCas-Guide-CRISPRa

  GA109186G3, IFT81 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001143779, NM_014055, NM_031473, NM_001347946, NM_001347947, NM_001347948, NR_144949, NR_144950, NR_144951, NR_144952
• Synonyms: CDV-1; CDV-1R; CDV1; CDV1R; DV1
• Summary: The protein encoded by this gene, together with IFT74, forms a tubulin-binding module of intraflagellar transport complex B. This module is involved in transport of tubulin within the cilium, and the encoded protein is required for ciliogenesis. Mutations in this gene are a cause of short-rib polydactyly syndromes. [provided by RefSeq, Dec 2016]