Human C13orf15 (RGCC) activation kit by CRISPRa

CAT#: GA109189

RGCC CRISPRa kit - CRISPR gene activation of human regulator of cell cycle

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: RGCC
• Locus ID: 28984
• Kit Components:

  GA109189G1, RGCC gRNA vector 1 in pCas-Guide-CRISPRa

  GA109189G2, RGCC gRNA vector 2 in pCas-Guide-CRISPRa

  GA109189G3, RGCC gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_014059
• Synonyms: bA157L14.2; C13orf15; RGC-32; RGC32
• Summary: This gene is thought to regulate cell cycle progression. It is induced by p53 in response to DNA damage, or by sublytic levels of complement system proteins that result in activation of the cell cycle. The encoded protein localizes to the cytoplasm during interphase and to centrosomes during mitosis. The protein forms a complex with polo-like kinase 1. The protein also translocates to the nucleus in response to treatment with complement system proteins, and can associate with and increase the kinase activity of cell division cycle 2 protein. In different assays and cell types, overexpression of this protein has been shown to activate or suppress cell cycle progression. [provided by RefSeq, Jul 2008]