Human C1GALT1C1 activation kit by CRISPRa

CAT#: GA109211

C1GALT1C1 CRISPRa kit - CRISPR gene activation of human C1GALT1 specific chaperone 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: C1GALT1C1
• Locus ID: 29071
• Kit Components:

  GA109211G1, C1GALT1C1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA109211G2, C1GALT1C1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA109211G3, C1GALT1C1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001011551, NM_014158, NM_152692
• Synonyms: C1GALT2; C38H2-L1; COSMC; HSPC067; MST143; TNPS
• Summary: This gene encodes a type II transmembrane protein that is similar to the core 1 beta1,3-galactosyltransferase 1, which catalyzes the synthesis of the core-1 structure, also known as Thomsen-Friedenreich antigen, on O-linked glycans. This gene product lacks the galactosyltransferase activity itself, but instead acts as a molecular chaperone required for the folding, stability and full activity of the core 1 beta1,3-galactosyltransferase 1. Mutations in this gene have been associated with Tn syndrome. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Dec 2009]