Human HEMK2 (N6AMT1) activation kit by CRISPRa

CAT#: GA109237

N6AMT1 CRISPRa kit - CRISPR gene activation of human N-6 adenine-specific DNA methyltransferase 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: N6AMT1
• Locus ID: 29104
• Kit Components:

  GA109237G1, N6AMT1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA109237G2, N6AMT1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA109237G3, N6AMT1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_013240, NM_182749, NR_047510
• Synonyms: C21orf127; HEMK2; m.HsaHemK2P; MTQ2; N6AMT; PRED28
• Summary: This gene encodes an N(6)-adenine-specific DNA methyltransferase. The encoded enzyme may be involved in the methylation of release factor I during translation termination. This enzyme is also involved in converting the arsenic metabolite monomethylarsonous acid to the less toxic dimethylarsonic acid. Alternative splicing pf this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 11. [provided by RefSeq, Jul 2014]