Human BRD7 activation kit by CRISPRa

CAT#: GA109248

BRD7 CRISPRa kit - CRISPR gene activation of human bromodomain containing 7

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: BRD7
• Locus ID: 29117
• Kit Components:

  GA109248G1, BRD7 gRNA vector 1 in pCas-Guide-CRISPRa

  GA109248G2, BRD7 gRNA vector 2 in pCas-Guide-CRISPRa

  GA109248G3, BRD7 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001173984, NM_013263
• Synonyms: BP75; CELTIX1; NAG4
• Summary: This gene encodes a protein which is a member of the bromodomain-containing protein family. The product of this gene has been identified as a component of one form of the SWI/SNF chromatin remodeling complex, and as a protein which interacts with p53 and is required for p53-dependent oncogene-induced senescence which prevents tumor growth. Pseudogenes have been described on chromosomes 2, 3, 6, 13 and 14. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2010]