Human USP25 activation kit by CRISPRa

CAT#: GA109260

USP25 CRISPRa kit - CRISPR gene activation of human ubiquitin specific peptidase 25

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: USP25
• Locus ID: 29761
• Kit Components:

  GA109260G1, USP25 gRNA vector 1 in pCas-Guide-CRISPRa

  GA109260G2, USP25 gRNA vector 2 in pCas-Guide-CRISPRa

  GA109260G3, USP25 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001283041, NM_001283042, NM_013396, NM_001352560, NM_001352561
• Synonyms: USP21
• Summary: Ubiquitin (MIM 191339) is a highly conserved 76-amino acid protein involved in regulation of intracellular protein breakdown, cell cycle regulation, and stress response. Ubiquitin is released from degraded proteins by disassembly of the polyubiquitin chains, which is mediated by ubiquitin-specific proteases (USPs), such as USP25 (Valero et al., 1999 [PubMed 10644437]). [supplied by OMIM, Mar 2008]