Human Activator of basal transcription 1 (ABT1) activation kit by CRISPRa

CAT#: GA109266

ABT1 CRISPRa kit - CRISPR gene activation of human activator of basal transcription 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ABT1
• Locus ID: 29777
• Kit Components:

  GA109266G1, ABT1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA109266G2, ABT1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA109266G3, ABT1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_013375
• Synonyms: hABT1
• Summary: Basal transcription of genes by RNA polymerase II requires the interaction of TATA-binding protein (TBP) with the core region of class II promoters. Studies in mouse suggest that the protein encoded by this gene likely activates basal transcription from class II promoters by interaction with TBP and the class II promoter DNA. [provided by RefSeq, Jul 2008]