Human SEC61A (SEC61A1) activation kit by CRISPRa

CAT#: GA109317

SEC61A1 CRISPRa kit - CRISPR gene activation of human SEC61 translocon alpha 1 subunit

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SEC61A1
• Locus ID: 29927
• Kit Components:

  GA109317G1, SEC61A1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA109317G2, SEC61A1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA109317G3, SEC61A1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_013336
• Synonyms: HSEC61; SEC61; SEC61A
• Summary: The protein encoded by this gene belongs to the SECY/SEC61- alpha family. It appears to play a crucial role in the insertion of secretory and membrane polypeptides into the endoplasmic reticulum. This protein found to be tightly associated with membrane-bound ribosomes, either directly or through adaptor proteins. This gene encodes an alpha subunit of the heteromeric SEC61 complex, which also contains beta and gamma subunits. [provided by RefSeq, Jul 2008]