Human SH3KBP1 activation kit by CRISPRa

CAT#: GA109376

SH3KBP1 CRISPRa kit - CRISPR gene activation of human SH3 domain containing kinase binding protein 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SH3KBP1
• Locus ID: 30011
• Kit Components:

  GA109376G1, SH3KBP1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA109376G2, SH3KBP1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA109376G3, SH3KBP1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001024666, NM_001184960, NM_031892, NM_001353890, NM_001353891, NM_001353892, NM_001353893, NM_001353894, NM_001353895, NM_001353897
• Synonyms: CD2BP3; CIN85; GIG10; HSB-1; HSB1; MIG18
• Summary: This gene encodes an adapter protein that contains one or more N-terminal Src homology domains, a proline rich region and a C-terminal coiled-coil domain. The encoded protein facilitates protein-protein interactions and has been implicated in numerous cellular processes including apoptosis, cytoskeletal rearrangement, cell adhesion and in the regulation of clathrin-dependent endocytosis. Alternate splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2017]