Human RAX activation kit by CRISPRa

CAT#: GA109380

RAX CRISPRa kit - CRISPR gene activation of human retina and anterior neural fold homeobox

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: RAX
• Locus ID: 30062
• Kit Components:

  GA109380G1, RAX gRNA vector 1 in pCas-Guide-CRISPRa

  GA109380G2, RAX gRNA vector 2 in pCas-Guide-CRISPRa

  GA109380G3, RAX gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_013435
• Synonyms: MCOP3; RX
• Summary: This gene encodes a homeobox-containing transcription factor that functions in eye development. The gene is expressed early in the eye primordia, and is required for retinal cell fate determination and also regulates stem cell proliferation. Mutations in this gene have been reported in patients with defects in ocular development, including microphthalmia, anophthalmia, and coloboma. [provided by RefSeq, Oct 2009]