Human Cornulin (CRNN) activation kit by CRISPRa

CAT#: GA109411

CRNN CRISPRa kit - CRISPR gene activation of human cornulin

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CRNN
• Locus ID: 49860
• Kit Components:

  GA109411G1, CRNN gRNA vector 1 in pCas-Guide-CRISPRa

  GA109411G2, CRNN gRNA vector 2 in pCas-Guide-CRISPRa

  GA109411G3, CRNN gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_016190
• Synonyms: C1orf10; DRC1; PDRC1; SEP53
• Summary: This gene encodes a member of the "fused gene" family of proteins, which contain N-terminus EF-hand domains and multiple tandem peptide repeats. The encoded protein contains two EF-hand Ca2+ binding domains in its N-terminus and two glutamine- and threonine-rich 60 amino acid repeats in its C-terminus. This gene, also known as squamous epithelial heat shock protein 53, may play a role in the mucosal/epithelial immune response and epidermal differentiation. [provided by RefSeq, Jan 2009]