Human MAP4K6 (MINK1) activation kit by CRISPRa

CAT#: GA109417

MINK1 CRISPRa kit - CRISPR gene activation of human misshapen like kinase 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: MINK1
• Locus ID: 50488
• Kit Components:

  GA109417G1, MINK1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA109417G2, MINK1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA109417G3, MINK1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001024937, NM_001321236, NM_015716, NM_153827, NM_170663
• Synonyms: B55; MAP4K6; MINK; YSK2; ZC3
• Summary: This gene encodes a serine/threonine kinase belonging to the germinal center kinase (GCK) family. The protein is structurally similar to the kinases that are related to NIK and may belong to a distinct subfamily of NIK-related kinases within the GCK family. Studies of the mouse homolog indicate an up-regulation of expression in the course of postnatal mouse cerebral development and activation of the cJun N-terminal kinase (JNK) and the p38 pathways. [provided by RefSeq, Mar 2016]