Human DUOX2 activation kit by CRISPRa

CAT#: GA109419

DUOX2 CRISPRa kit - CRISPR gene activation of human dual oxidase 2


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USD 1,290.00

2 Weeks*

Size
    • 1 kit

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Specifications

Product Data
Format 3gRNAs, 1 scramble ctrl and 1 enhancer vector
Symbol DUOX2
Locus ID 50506
Kit Components

GA109419G1, DUOX2 gRNA vector 1 in pCas-Guide-CRISPRa

GA109419G2, DUOX2 gRNA vector 2 in pCas-Guide-CRISPRa

GA109419G3, DUOX2 gRNA vector 3 in pCas-Guide-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100058

Disclaimer The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_014080, NM_001363711
Synonyms LNOX2; NOXEF2; P138-TOX; TDH6; THOX2
Summary The protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter, thyroperoxidase, and a peroxide generating system that includes this encoded protein and DUOX1. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain. [provided by RefSeq, Jul 2008]

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.