Human IL20 activation kit by CRISPRa

CAT#: GA109426

IL20 CRISPRa kit - CRISPR gene activation of human interleukin 20

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: IL20
• Locus ID: 50604
• Kit Components:

  GA109426G1, IL20 gRNA vector 1 in pCas-Guide-CRISPRa

  GA109426G2, IL20 gRNA vector 2 in pCas-Guide-CRISPRa

  GA109426G3, IL20 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_018724
• Synonyms: IL-20; IL10D; ZCYTO10
• Summary: The protein encoded by this gene is a cytokine structurally related to interleukin 10 (IL10). This cytokine has been shown to transduce its signal through signal transducer and activator of transcription 3 (STAT3) in keratinocytes. A specific receptor for this cytokine is found to be expressed in skin and upregulated dramatically in psoriatic skin, suggesting a role for this protein in epidermal function and psoriasis. [provided by RefSeq, Jul 2008]