Human NSDHL activation kit by CRISPRa

CAT#: GA109455

NSDHL CRISPRa kit - CRISPR gene activation of human NAD(P) dependent steroid dehydrogenase-like

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NSDHL
• Locus ID: 50814
• Kit Components:

  GA109455G1, NSDHL gRNA vector 1 in pCas-Guide-CRISPRa

  GA109455G2, NSDHL gRNA vector 2 in pCas-Guide-CRISPRa

  GA109455G3, NSDHL gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001129765, NM_015922
• Synonyms: H105E3; SDR31E1; XAP104
• Summary: The protein encoded by this gene is localized in the endoplasmic reticulum and is involved in cholesterol biosynthesis. Mutations in this gene are associated with CHILD syndrome, which is a X-linked dominant disorder of lipid metabolism with disturbed cholesterol biosynthesis, and typically lethal in males. Alternatively spliced transcript variants with differing 5' UTR have been found for this gene. [provided by RefSeq, Jul 2008]