Human IMPG2 activation kit by CRISPRa

CAT#: GA109478

IMPG2 CRISPRa kit - CRISPR gene activation of human interphotoreceptor matrix proteoglycan 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: IMPG2
• Locus ID: 50939
• Kit Components:

  GA109478G1, IMPG2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA109478G2, IMPG2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA109478G3, IMPG2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_016247
• Synonyms: IPM200; RP56; SPACRCAN; VMD5
• Summary: The protein encoded by this gene binds chondroitin sulfate and hyaluronan and is a proteoglycan. The encoded protein plays a role in the organization of the interphotoreceptor matrix and may promote the growth and maintenance of the light-sensitive photoreceptor outer segment. Defects in this gene are a cause of retinitis pigmentosa type 56 and maculopathy, IMPG2-related. [provided by RefSeq, Mar 2011]