Human FOXP3 activation kit by CRISPRa

CAT#: GA109480

FOXP3 CRISPRa kit - CRISPR gene activation of human forkhead box P3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: FOXP3
• Locus ID: 50943
• Kit Components:

  GA109480G1, FOXP3 gRNA vector 1 in pCas-Guide-CRISPRa

  GA109480G2, FOXP3 gRNA vector 2 in pCas-Guide-CRISPRa

  GA109480G3, FOXP3 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001114377, NM_014009
• Synonyms: AIID; DIETER; IPEX; JM2; PIDX; XPID
• Summary: The protein encoded by this gene is a member of the forkhead/winged-helix family of transcriptional regulators. Defects in this gene are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX), also known as X-linked autoimmunity-immunodeficiency syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]