Human ASCC1 activation kit by CRISPRa
CAT#: GA109492
ASCC1 CRISPRa kit - CRISPR gene activation of human activating signal cointegrator 1 complex subunit 1
Find the corresponding CRISPRi Inhibitor Kit
USD 1,290.00
2 Weeks*
Specifications
Product Data | |
Format | 3gRNAs, 1 scramble ctrl and 1 enhancer vector |
Symbol | ASCC1 |
Locus ID | 51008 |
Kit Components | GA109492G1, ASCC1 gRNA vector 1 in pCas-Guide-CRISPRa GA109492G2, ASCC1 gRNA vector 2 in pCas-Guide-CRISPRa GA109492G3, ASCC1 gRNA vector 3 in pCas-Guide-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100058 |
Disclaimer | The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001198798, NM_001198799, NM_001198800, NM_015947, NR_045564, NM_001369086, NM_001369085, NM_001369087, NM_001369088, NM_001369090, NM_001369091, NM_001369095, NM_001369098, NM_001369099, NM_001369102, NM_001369107, NM_001369110, NM_001369111, NM_001369112, NM_001369089, NM_001369092, NM_001369093, NM_001369094, NM_001369096, NM_001369097, NM_001369100, NM_001369101, NM_001369103, NM_001369104, NM_001369105, NM_001369106, NM_001369108, NM_001369109 |
Synonyms | ASC1p50; CGI-18; p50 |
Summary | This gene encodes a subunit of the activating signal cointegrator 1 (ASC-1) complex. The ASC-1 complex is a transcriptional coactivator that plays an important role in gene transactivation by multiple transcription factors including activating protein 1 (AP-1), nuclear factor kappa-B (NF-kB) and serum response factor (SRF). The encoded protein contains an N-terminal KH-type RNA-binding motif which is required for AP-1 transactivation by the ASC-1 complex. Mutations in this gene are associated with Barrett esophagus and esophageal adenocarcinoma. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011] |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN401872 | ASCC1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
USD 1,290.00 |
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