Human POLR1D activation kit by CRISPRa

CAT#: GA109547

POLR1D CRISPRa kit - CRISPR gene activation of human RNA polymerase I and III subunit D

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: POLR1D
• Locus ID: 51082
• Kit Components:

  GA109547G1, POLR1D gRNA vector 1 in pCas-Guide-CRISPRa

  GA109547G2, POLR1D gRNA vector 2 in pCas-Guide-CRISPRa

  GA109547G3, POLR1D gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001206559, NM_015972, NM_152705
• Synonyms: AC19; POLR1C; RPA9; RPA16; RPAC2; RPC16; RPO1-3; TCS2
• Summary: The protein encoded by this gene is a component of the RNA polymerase I and RNA polymerase III complexes, which function in the synthesis of ribosomal RNA precursors and small RNAs, respectively. Mutations in this gene are a cause of Treacher Collins syndrome (TCS), a craniofacial development disorder. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2011]