Human CRYL1 activation kit by CRISPRa

CAT#: GA109549

CRYL1 CRISPRa kit - CRISPR gene activation of human crystallin lambda 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CRYL1
• Locus ID: 51084
• Kit Components:

  GA109549G1, CRYL1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA109549G2, CRYL1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA109549G3, CRYL1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_015974, NM_001363647
• Synonyms: GDH; HEL30; lambda-CRY
• Summary: The uronate cycle functions as an alternative glucose metabolic pathway, accounting for about 5% of daily glucose catabolism. The product of this gene catalyzes the dehydrogenation of L-gulonate into dehydro-L-gulonate in the uronate cycle. The enzyme requires NAD(H) as a coenzyme, and is inhibited by inorganic phosphate. A similar gene in the rabbit is thought to serve a structural role in the lens of the eye. [provided by RefSeq, Jul 2008]