Human ABHD5 activation kit by CRISPRa

CAT#: GA109563

ABHD5 CRISPRa kit - CRISPR gene activation of human abhydrolase domain containing 5

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ABHD5
• Locus ID: 51099
• Kit Components:

  GA109563G1, ABHD5 gRNA vector 1 in pCas-Guide-CRISPRa

  GA109563G2, ABHD5 gRNA vector 2 in pCas-Guide-CRISPRa

  GA109563G3, ABHD5 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_016006, NM_001355186, NM_001365649, NM_001365650, NR_158560
• Synonyms: CDS; CGI58; IECN2; NCIE2
• Summary: The protein encoded by this gene belongs to a large family of proteins defined by an alpha/beta hydrolase fold, and contains three sequence motifs that correspond to a catalytic triad found in the esterase/lipase/thioesterase subfamily. It differs from other members of this subfamily in that its putative catalytic triad contains an asparagine instead of the serine residue. Mutations in this gene have been associated with Chanarin-Dorfman syndrome, a triglyceride storage disease with impaired long-chain fatty acid oxidation. [provided by RefSeq, Jul 2008]