Human Bif (SH3GLB1) activation kit by CRISPRa

CAT#: GA109564

SH3GLB1 CRISPRa kit - CRISPR gene activation of human SH3 domain containing GRB2 like, endophilin B1


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USD 1,290.00

2 Weeks*

Size
    • 1 kit

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Specifications

Product Data
Format 3gRNAs, 1 scramble ctrl and 1 enhancer vector
Symbol SH3GLB1
Locus ID 51100
Kit Components

GA109564G1, SH3GLB1 gRNA vector 1 in pCas-Guide-CRISPRa

GA109564G2, SH3GLB1 gRNA vector 2 in pCas-Guide-CRISPRa

GA109564G3, SH3GLB1 gRNA vector 3 in pCas-Guide-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100058

Disclaimer The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001206651, NM_001206652, NM_001206653, NM_016009
Synonyms Bif-1; CGI-61; dJ612B15.2; PPP1R70
Summary This gene encodes a SRC homology 3 domain-containing protein. The encoded protein interacts with the proapoptotic member of the Bcl-2 family, Bcl-2-associated X protein (Bax) and may be involved in regulating apoptotic signaling pathways. This protein may also be involved in maintaining mitochondrial morphology. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011]

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.