Human IER3IP1 activation kit by CRISPRa

CAT#: GA109586

IER3IP1 CRISPRa kit - CRISPR gene activation of human immediate early response 3 interacting protein 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: IER3IP1
• Locus ID: 51124
• Kit Components:

  GA109586G1, IER3IP1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA109586G2, IER3IP1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA109586G3, IER3IP1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_016097
• Synonyms: HSPC039; MEDS; PRO2309
• Summary: This gene encodes a small protein that is localized to the endoplasmic reticulum (ER) and may play a role in the ER stress response by mediating cell differentiation and apoptosis. Transcription of this gene is regulated by tumor necrosis factor alpha and specificity protein 1 (Sp1). Mutations in this gene may play a role in microcephaly, epilepsy, and diabetes syndrome (MEDS), and a pseudogene of this gene is located on the long arm of chromosome 12. [provided by RefSeq, Dec 2011]